| breast cancer - HER2-positive | |||
| es-BC - HER2 positive - (neo)adjuvant (NA) | la/mBC - HER2 positive - 1st Line (L1) | la/mBC - HER2 positive - 2nd Line (L2) | |
| HER2 inhibitor | |||
| neratinib based treatment | |||
| neratinib | ExteNET | ||
| neratinib plus capecitabine | NALA NALA ... | ||
| pertuzumab based treatment | |||
| pertuzumab plus trastuzumab | IMpassion-050 IMpassion-050 IMpassion-050 | PERTAIN | |
| pertuzumab plus trastuzumab plus docetaxel | PUFFIN CLEOPATRA | ||
| trastuzumab based treatment | |||
| trastuzumab plus endocrine therapy | SYSUCC-002 | ||
| trastuzumab plus epirubicin and cyclophosphamide followed by docetaxel | GeparQuinto | ||
| tucatinib based treatment | |||
| tucatinib plus trastuzumab plus capecitabine | HER2CLIMB HER2CLIMB ... | ||
Study type:
delta: difference in rate or median (if available)
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