meta
|
evidence
oncology
Living systematic review and meta-analysis
AKT inhibitor
capivasertib based treatment
capivasertib plus paclitaxel
ipatasertib based treatment
ipatasertib plus paclitaxel
antibody–drug conjugate
sacituzumab govitecan
trastuzumab deruxtecan
trastuzumab emtansine
trastuzumab emtasine plus endocrine therapy
aurora kinase inhibitors
alisertib plus paclitaxel
biguanide
metformin
celecoxib plus endocrine therapy
chemotherapy
non platinum-based chemotherapy
microtubul inhibitor
eribulin
nucleoside analogues (pyrimidine/purine)
capecitabine
taxanes
paclitaxel
nab-paclitaxel
paclitaxel followed by doxorubicin plus cyclophosphamide
pegylated liposomal doxorubicin and cyclophosphamide
Standard of Care (SoC)
cyclin inhibitor
abemaciclib based treatment
abemaciclib plus aromatase inhibitor
abemaciclib plus endocrine therapy
abemaciclib plus fulvestrant
dalpiciclib plus fulvestrant
palbociclib based treatment
palbociclib
palbociclib plus endocrine therapy
palbociclib plus fulvestrant
palbociclib plus letrozole
ribociclib based treatment
ribociclib plus endocrine therapy
ribociclib plus fulvestrant
ribociclib plus letrozole
endocrine therapy
androgen deprivation therapy (ADT)
abiraterone plus ADT
abiraterone plus docetaxel plus ADT
apalutamide plus ADT
darolutamide plus doxetaxel plus ADT
docetaxel plus ADT
enzalutamide
enzalutamide plus ADT
gene alteration target therapy
BRAF gene alteration targeted therapy
BRAF inhibitor
combined BRAF-MEK inhibitors
trametinib plus dabrafenib
KRAS gene alteration targeted therapy
sotorasib
MET gene alteration targeted therapy
capmatinib
NTRK gene alteration targeted therapy
entrectinib
larotrectinib
RET gene alteration targeted therapy
pralsetinib
selpercatinib
HDAC inhibitor
entinostat plus exemestane
tucidinostat based treatment
tucidinostat plus exemestane
HER inhibitor
EGFR inhibitor
afatinib based treatment
afatinib plus vinorelbine
HER2 inhibitor
neratinib based treatment
neratinib
neratinib plus capecitabine
pertuzumab based treatment
pertuzumab plus trastuzumab
pertuzumab plus trastuzumab plus docetaxel
trastuzumab based treatment
docetaxel plus carboplatin with trastuzumab followed by trastuzumab
doxorubicin plus cyclophosphamide followed by docetaxel plus trastuzumab
trastuzumab plus endocrine therapy
trastuzumab plus epirubicin and cyclophosphamide followed by docetaxel
tucatinib based treatment
tucatinib plus trastuzumab plus capecitabine
TKI anti HER1/EGFR and HER2/neu
lapatinib based treatment
lapatinib
lapatinib plus capecitabine
lapatinib plus fulvestrant
lapatinib plus letrozole
lapatinib plus paclitaxel
lapatinib plus trastuzumab
lapatinib plus trastuzumab plus paclitaxel
IGF-1R inhibitors
dalotuzumab plus ridaforolimus plus exemestane
ganitumab plus endocrine therapy
immune chekpoint inhibitors
anti-CTLA-4
ipilimumab based treatment
ipilimumab alone
Ipilimumab (10 mg/kg)
ipilimumab plus gp100
ipilimumab plus SoC
tremelimumab
anti-PD-(L)1
atezolizumab based treatment
atezolizumab alone
atezolizumab plus bevacizumab
atezolizumab plus bevacizumab plus carboplatin plus paclitaxel
atezolizumab plus cabozantinib
atezolizumab plus carboplatin plus nab-paclitaxel
atezolizumab plus carboplatin plus paclitaxel
atezolizumab plus cometinib
atezolizumab plus FOLFOXIRI plus bevacizumab
atezolizumab plus nab-paclitaxel
atezolizumab plus nab-paclitxel followed by doxorubicin plus cyclophosphamide
atezolizumab plus paclitaxel
atezolizumab plus pemetrexed and platin
atezolizumab plus SoC
avelumab based treatment
avelumab alone
avelumab plus axitinib
avelumab plus pegylated liposomal doxorubicin
avelumab plus SoC
camrelizumab based treatment
camrelizumab alone
cemiplimab
dostarlimab based treatment
dostarlimab plus soC
durvalumab based treatment
durvalumab alone
durvalumab plus bevacizumab
durvalumab plus etoposide and platin
durvalumab plus olaparib plus SoC
durvalumab plus osimertinib
durvalumab plus SoC
nivolumab based treatment
nivolumab alone
nivolumab plus cabozantinib
nivolumab plus SoC
nivolumab followed by ipilimumab
pembrolizumab based treatment
pembrolizumab alone
pembrolizumab (10mg/kg)
pembrolizumab (10mg/kg) 2 weeks
pembrolizumab (2mg/kg)
pembrolizumab and pemetrexed plus platin
pembrolizumab plus 5FU plus platin
pembrolizumab plus axitinib
pembrolizumab plus lenalidomide and dexamethasone
pembrolizumab plus lenvatinib
pembrolizumab plus paclitxel followed by doxorubicin plus cyclophosphamide
pembrolizumab plus pomalidomide and dexamethasone
pembrolizumab plus SoC
sintilimab based treatment
sintilimab
sintillimab plus SoC
Tislelizumab
toripalimab
Immune checkpoint association
durvalumab plus tremelimumab
durvalumab plus tremelimumab plus SoC
nivolumab plus ipilimumab
nivolumab plus ipilimumab plus SoC
pembrolizumab plus ipilimumab
relatlimab plus nivolumab
Immunostimulant
vaccine
AE37 vaccine plus GM-CSF
GP2 vaccine plus GM-CSF
OBI-822/OBI-821 plus cyclophosphamide
inetetamab plus vinorelbine
mTOR inhibitors
everolimus
lenvatinib plus everolimus
sapanisertib plus fulvestrant
phosphoinositide 3-kinase (PI3K) inhibitor
alpelisib based treatment
alpelisib plus fulvestrant
alpelisib plus letrozole
buparlisib based treatment
buparlisib plus fulvestrant
buparlisib plus letrozole
taselisib based treatment
taselisib plus letrozole
poly ADP-ribose polymerase (PARP) inhibitor
niraparib
olaparib
rucaparib
talazoparib
veliparib plus paclitaxel plus carboplatin
target therapy
margetuximab based treatment
margetuximab plus chemotherapy
multikinase inhibitor
nintedanib
VEGF(R) inhibitor
bevacizumab based treatment
bevacizumab
bevacizumab plus trastuzumab plus docetaxel
cediranib plus fulvestrant
lenvatinib
lenvatinib in association