table network network 2
demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only observational study
COVID 19 hospitalized
COVID 19 hospitalizedCOVID 19 all comersCOVID-19 mild to moderateCOVID-19 severe or critically
Immunostimulants drugs
convalescent plasma treatment ConPlas-19 CPC-SARS COPLA-II trial Bennett-Guerrero COP-COVID-19 NCT04403477 ... CONTAIN COVID-19 NCT04442191 LACCPT ASCOT PERUCONPLASMA Co-CLARITY Baldeon Abolghasemi PC/COVID-19 DAWN-Plasma RECOVERY ... NCT04528368 Menichetti NCT04397757 NCT04385199 Salman Holm K ConCOVID ... Salazar PLACO-COVID Kirenga CCAP-2 CONCOR-1 CONFIDENT LIFESAVER Libster PLACID CP-COVID-19 RECOVER ILBS-COVID-02 ... PICP19 ... Pouladzadeh Rasheed AlQahtani Duan Hegerova O’Donnell PlasmAr Sekine ... Li Sean Joyner CAPSID REMAP-CAP ... Bihariesingh-Sanchit ... Ray
Early convalescent plasma. Balcells
immunoglobulin therapy Sakoulas Parikh Raman Tabarsi Gharebaghi
interferon Wang ... Wang Cai -FAVIPIRAVIR Cai -FAVIPIRAVIR
IFN beta-1a SOLIDARITY ... Kalil ... Davoudi-Monfared Darazam ...
high-dose IFN beta-1a Darazam
IFN beta-1b Darazam ... Rahmani
IFN gamma Esquivel-Moynelo
inhaled interferon
IFN alpha
pegylated interferon-α2b Pandit Shashi Bhushan
recombinant super-compound interferon rSIFN-co Li
SNG001 inhaled interferon beta SPRINTER Synairgen SG016
interferon / TFF2 Fu
peginterferon Jagannathan
PNB001 Lattmann
neutralizing antibody ITAC
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences) ACTIV-3 ...
bamlanivimab monotherapy ACTIV-3/TICO LY-CoV555
casirivimab/imdevimab (Ronapreve) RECOVERY ... Suzuki Somersan-Karakaya ...
cilgavimab and tixagevimab (Evusheld) ACTIV-3/TICO ... Chen
equine polyclonal antibodies INM005 Lopardo
sotrovimab (Xevudy; VIR-7831) ACTIV-3/ TICO ...

7 studies excluded by filtering options 2

5405 Ahn, 2020 200excludedrisk of bias not avaialble
5408 Shen, 2020 200excludedrisk of bias not avaialble
5409 Ye, 2020 200excludedrisk of bias not avaialble
5410 Zhang, 2020 200excludedrisk of bias not avaialble
5411 Zhang, 2020 200excludedrisk of bias not avaialble
5569 Dai W, 2020 2134excludednot a RCThigh risk of bias
10178 Bargay-Lleonart, 2022 210excludedrisk of bias not avaialble

 

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