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meta|IO

Evidence base on efficacy and safety of
Immuno-Oncology drugs

Global living systematic review and meta-analysis of RCTs

Pathology

billiary tract cancer - 1st line

3 trials

breast cancer - adjuvant

13 trials

breast cancer - HER2-positive

23 trials

breast cancer - HR positive

46 trials

breast cancer - triple negative

30 trials

breast cancer HER 2 negative

2 trials

metastatic/advanced - breast cancer

1 trials

refractory classic Hodgkin lymphoma

1 trials

metastatic/advanced - colorectal cancer

13 trials

endometrial cancer - adjuvant

1 trials

metastatic/advanced - esophageal cancer

5 trials

metastatic/advanced mGC or mGEJC

14 trials

metastatic glioblastoma - 1st line

1 trials

locally advanced

1 trials

metastatic-recurrent HNSCC

13 trials

metastatic/advanced hepatocellular cancer

15 trials

locally advanced NSCLC - adjuvant

1 trials

locally advanced NSCLC - maintenance

1 trials

metastatic/advanced NSCLC - 1st line

34 trials

metastatic/advanced NSCLC - 2nd line

17 trials

NSCLC neoadjuvant setting

1 trials

Extensive stage SCLC

7 trials

limited stage SCLC

1 trials

metastatic/adv melanoma

34 trials

malignant mesothelioma - 1st line

1 trials

malignant mesothelioma - 2nd line

2 trials

multiple myeloma - 1st line

1 trials

multiple myeloma - 2nd line

1 trials

metastatic/advanced OC - 1st line

3 trials

metastatic/advanced OC - 2nd line

3 trials

metastatic/advanced OC - maintenance

2 trials

castration-resistant prostate cancer

3 trials

metastatic, hormone-sensitive prostate cancer

11 trials

metastatic/advanced RCC - adjuvant

3 trials

metastatic/advanced RCC - 1st line

16 trials

metastatic/advanced RCC - 2nd line

2 trials

metastatic/advanced UC - 1st Line

8 trials

metastatic/advanced UC - 2nd Line

5 trials

metastatic/advanced UC - maintenance

2 trials

muscular invasive bladder cancer

3 trials

450
treatments 		  383
studies 		  1302
references
This project is supported by H2020 Qualitop, an EU-funded project, Hospices Civils de Lyon and CNRS UMR5558 LBBE.
     

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