| Study |  | Exclusion reasons | Remarks | Reference(s) |  | 
            
            
                | study 101 dose finding, 2020 | non randomized controlled trial | no control group | phase 1 | Anderson EJ  N Engl J Med 2020 Sep 29. 10.1056/NEJMoa2028436 Jackson LA  N Engl J Med 2020 Nov 12;383(20):1920-1931. 10.1056/NEJMoa2022483 |  | 
            
            
                | Montgomery, 2021 | retrospective cohort | no control group |  | Montgomery J et al.  JAMA Cardiol 10.1001/jamacardio.2021.2833 |  | 
            
            
                | Ruddy, 2021 | case series | no control group |  | Ruddy JA  AIDS 2021 Sep 1;35(11):1872-1874. 10.1097/QAD.0000000000002945 |  | 
            
            
                | Burns, 2022 | - | no control group |  | Burns MD et al.  medrxiv;2022.01.05.22268617v1 10.1101/2022.01.05.22268617 |  | 
            
            
                | Kawasuji, 2022 | - | no control group |  | Kawasuji H et al.  medrxiv;2022.02.23.22271433v1 10.1101/2022.02.23.22271433 |  | 
            
            
                | Falsey, 0 | - | no control group |  | Falsey AR et al.  New England Journal of Medicine 10.1056/NEJMc2113468 |  | 
            
            
                | BioNTech phase 2 (Walsh), 2020 | randomized controlled trial | no clinically relevant endpoint | phase 1-2 ; dose-escalation : 13 groups of 15 participants |  |  | 
            
            
                | Moderna preclinical (Corbett), 2020 | randomized controlled trial | other |  | Corbett KS  N Engl J Med 2020 Oct 15;383(16):1544-1555. 10.1056/NEJMoa2024671 |  | 
            
            
                | Pfizer 16-25 years phase 3, 0 | randomized controlled trial | other | very preliminary results from a press release |  |  | 
            
            
                | Ou, 2021 | case series | other | safety and reactogenicity, no immunogenicity | Ou MT  Transplantation 2021 Apr 9. 10.1097/TP.0000000000003780 |  | 
            
            
                | Molteni, 2022 | - | other | modelling study | Molteni E et al.  medrxiv;2022.03.13.22272176v1 10.1101/2022.03.13.22272176 |  |