All patients
corticosteroids: no corticosteroids: yes critical disease severe disease
Immunosuppressants drugs in COVID 19 all comers - Summary of results Outcome TE 95% CI n k I2 ROB Pub. bias death D28detailed results RECOVERY, 2022 0.87 [0.77; 0.98]
0.87 [0.77 ; 0.98 ] RECOVERY, 2022 1 0% 8,156 NA not evaluable death or transfer to ICUdetailed results BACC Bay Tocilizumab Trial, 2020 0.97 [0.50; 1.88]
0.97 [0.50 ; 1.88 ] BACC Bay Tocilizumab Trial, 2020 1 0% 242 NA not evaluable deathsdetailed results BACC Bay Tocilizumab Trial, 2020 1.52 [0.41; 5.62]
RECOVERY, 2022 0.87 [0.77; 0.98]
0.87 [0.78 ; 0.99 ] BACC Bay Tocilizumab Trial, 2020, RECOVERY, 2022 2 0% 8,398 moderate not evaluable clinical deteriorationdetailed results BACC Bay Tocilizumab Trial, 2020 1.11 [0.59; 2.09]
1.11 [0.59 ; 2.09 ] BACC Bay Tocilizumab Trial, 2020 1 0% 242 NA not evaluable clinical improvementdetailed results BACC Bay Tocilizumab Trial, 2020 1.06 [0.80; 1.41]
1.06 [0.80 ; 1.41 ] BACC Bay Tocilizumab Trial, 2020 1 0% 242 NA not evaluable death or ventilationdetailed results BACC Bay Tocilizumab Trial, 2020 0.83 [0.38; 1.81]
RECOVERY, 2022 0.90 [0.81; 0.99]
0.90 [0.81 ; 0.99 ] BACC Bay Tocilizumab Trial, 2020, RECOVERY, 2022 2 0% 8,147 moderate not evaluable mechanical ventilationdetailed results RECOVERY, 2022 0.87 [0.74; 1.02]
0.87 [0.74 ; 1.02 ] RECOVERY, 2022 1 0% 7,905 NA not evaluable serious adverse eventsdetailed results BACC Bay Tocilizumab Trial, 2020 1.21 [0.58; 2.53]
1.21 [0.58 ; 2.53 ] BACC Bay Tocilizumab Trial, 2020 1 0% 242 NA not evaluable 0.5 2.0 1.0 relative treatment effect www.metaEvidence.org 2025-03-09 15:55 +01:00
TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers);
k: number of studies; n: total number of patients;
ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1;
studied treatment is better when TE < 1;
pathologies: 94
- treatments: 596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526
- roots T: 290