meta
|
evidence
oncology
Living systematic review and meta-analysis
breast cancer - HR positive
es-BC - HR positive - (neo)adjuvant (NA)
2
es-BC - HR-positive - 1st line (L1)
1
la/mBC - HR positive
3
la/mBC - HR positive - (neo)adjuvant (NA)
3
la/mBC - HR positive - NA - PIK3CA mutant
la/mBC - HR-positive - 1st line (L1)
13
la/mBC - HR positive - L1 - PIK3CA mutant
1
la/mBC - HR-positive - 2nd line (L2)
20
la/mBC - HR positive - L2 - all population
2
la/mBC - HR positive - L2 - PIK3CA mutant
1
All treatments
aurora kinase inhibitors
alisertib plus paclitaxel
biguanide
metformin
celecoxib plus endocrine therapy
chemotherapy
pegylated liposomal doxorubicin and cyclophosphamide
cyclin inhibitor
abemaciclib based treatment
abemaciclib plus fulvestrant
dalpiciclib plus fulvestrant
palbociclib based treatment
palbociclib plus fulvestrant
ribociclib based treatment
ribociclib plus endocrine therapy
ribociclib plus fulvestrant
HDAC inhibitor
entinostat plus exemestane
tucidinostat based treatment
tucidinostat plus exemestane
IGF-1R inhibitors
ganitumab plus endocrine therapy
immune chekpoint inhibitors
Immune checkpoint association
nivolumab plus ipilimumab
Immunostimulant
vaccine
OBI-822/OBI-821 plus cyclophosphamide
mTOR inhibitors
sapanisertib plus fulvestrant
phosphoinositide 3-kinase (PI3K) inhibitor
alpelisib based treatment
alpelisib plus fulvestrant
buparlisib based treatment
buparlisib plus fulvestrant
versus all
vs chemotherapy
vs non platinum-based chemotherapy
vs taxanes
vs paclitaxel
vs pegylated liposomal doxorubicin and cyclophosphamide
vs endocrine therapy
vs exemestane
vs fulvestrant
vs non active control
vs placebo
study list
mapping
overview
meta-analysis
forest plot
NMA
excluded
summary
GRADE
treatment
patients
risk of bias
overview
numeric
bar chart
forest plot
medians
frequency on treatment
benefit risk analysis
Study
study type
RCT
OBS
RCT + OBS
Pathology
T1
T0
Patients
sample sizes
ROB
Results
×
delta: difference in rate or median (if available)
×
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