| display ongoing studies | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Study | Ref. | Design | studied treatment | control treatment | patients | study risk of bias | sample sizes | Results | Bell's palsy S | appendicitis S | myocarditis S | pericarditis S | Guillain-Barré syndrome S | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
COVID-19 prophylaxis (excluding children) meta-analysis | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| BNT162b2 phase 3 (C4591001, Polack) NCT04368728 | RCT | Comirnaty (tozinameran - Pfizer/BIONTECH) | placebo | COVID-19 prophylaxis (excluding children) | some concern | 21720/21728 | conclusif | BNT162b2 phase 3 (C4591001, Polack)")' style='color: black;' class='popover-interpretation' data-toggle='popover' data-placement='bottom' data-html='true' data-trigger='hover' container='body' data-content="Bell's palsy safetyrelative treatment effect [95% CI]: 7.99 [0.42; 151.24] calc. 4/18801 (0.0%) vs. 0/18785 (0.0%) AE, unserious, unsolicited " > | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).
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