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Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID 19 all comers meta-analysis

Chen, ChiCTR2000030054 - Chloroquine
  ChiCTR2000030054		 RCTchloroquinestandard of careCOVID 19 all comershigh
18/12 inconclusive
    ChiCTR2000030054-HCQ (Chen)
          ChiCTR2000030054    		 RCThydroxychloroquinestandard of careCOVID 19 all comershigh
    		18/12 inconclusive
      Gautret et al. NRahydroxychloroquinecontrolCOVID 19 all comersserious
      		20/16 uncontrolled
      • [uncontrolled] virological cure (negative nasopharyngeal PCR): 70.0% (14/20)
      a viral load reduction/disappearance is claimed but the numerous methological limits preclude any strong conclusion

      PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
      Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

       

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