Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method
| Treament | Trials | |||||
|---|---|---|---|---|---|---|
| clinical deterioration | clinical improvement | deaths | viral clearance | |||
| angiotensin receptor blockers (ARBs) | OBS 0.77 [0.36; 1.64], 1 study, I2=0% inconclusive result | - | 0.47 [0.17; 1.29], 3 RCTs, I2=0% inconclusive result | - | ||
| discontinuation of ACEI/ARB | - | - | 0.92 [0.47; 1.77], 2 RCTs, I2=0% inconclusive result | - | ||
| angiotensin converting enzyme inhibitors (ACEIs) | 0 | - | - | - | - | |
| angiotensin-(1-7) | 0 | - | - | - | - | |
| continuation of ACEI/ARB | 0 | - | - | - | - | |
| RAS blocker withdrawal | 0 | - | - | - | - | |
| rhACE2 | 0 | - | - | - | - | |
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