Fingolimod

Table   Graphic     exposition period:

Congenital malformations
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Major congenital malformations0.85 [0.06, 12.12]30%2 studies674not evaluable ROB-
All congenital malformations (majors, minors, majors and minors, or unspecified)0.12 [0.00, 7.22]-1 study332not evaluable ROB-

Growth parameters and prematurity
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Preterm (< 37 weeks)1.32 [0.47, 3.69]0%2 studies19250not evaluable ROB-

Intrauterine deaths
Adverse outcome OR 95%CII2k No. casesNo. exposedpublication biasROBE-value
Elective/induced termination of pregnancy0.88 [0.16, 4.97]75%3 studies82136not evaluable ROB-
Early intrauterine death (< 22 weeks)0.77 [0.30, 2.00]0%2 studies28124not evaluable ROB-
Intrauterine deaths (as a whole or unspecified)1.30 [0.16, 10.24]-1 study5112not evaluable ROB-
Therapeutic terminations of pregnancy0.98 [0.06, 16.09]-1 study263not evaluable ROB-

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