Verapamil (versus unexposed)

Late intrauterine deaths (> 22 weeks)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S13992
R54950		 Weber-Schoendorfer, 2008 Stillbirths at least 1st trimester prospective cohort unexposed (general population or NOS) Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified 2.25 [0.27;19.02] C 1/58   6/776 7 58
ref
Total 1 studies 2.25 [0.27;19.02] 7 58
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Weber-Schoendorfer, 2008Weber-Schoendorfer, 2008 2.25[0.27; 19.02]7580%ROB confusion: criticalROB selection: moderateROB classification: moderateROB missing: moderateROB mesure: unclearROB reporting: moderate0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.25[0.27; 19.02]758 -NAWeber-Schoendorfer, 2008 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 2.25[0.27; 19.02]758 -NAWeber-Schoendorfer, 2008 1 Tags Adjustment   - No  - No 2.25[0.27; 19.02]758 -NAWeber-Schoendorfer, 2008 1 Indications Antihypertensive   - All hypertensions, any indications ...  - All hypertensions, any indications or not specified 2.25[0.27; 19.02]758 -NAWeber-Schoendorfer, 2008 1 All studiesAll studies 2.25[0.27; 19.02]758 -NAWeber-Schoendorfer, 2008 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 2.25[0.27; 19.02]758 -NAWeber-Schoendorfer, 2008 10.510.01.0