Celiprolol (versus unexposed) - Medication and Pregnancy KB

Celiprolol (versus unexposed) updated on 12-17-2024

All congenital malformations (majors, minors, majors and minors, or unspecified)

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S17479 R73486	Delteil, 2024	Major congenital malformations	at least 1st trimester	retrospective cohort (claims database)	unexposed (general population or NOS)	Adjustment: No Indications Antihypertensive: Only chronic indication (hypertension or cardiac)	6.65 [0.80;55.24] ^C	1/7 4,054/165,775	4,055	7		ref
					Total	1 studies	6.65 [0.80;55.24]		4,055	7
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded