Hydralazine (versus unexposed) updated on 03-11-2025

Small for gestational age (weight)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S14190
R55608		 Welt, 1981 Small for gestational age 2nd and/or 3rd trimester randomized controlled trial unexposed, sick Adjustment: Randomisation Indications Antihypertensive: Only chronic hypertension indication 7.00 [0.29;170.06] C 3/9   0/6 3 9
ref
Total 1 studies 7.00 [0.29;170.06] 3 9
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Welt, 1981Welt, 1981 7.00[0.29; 170.06]390%ROB confusion: lowROB selection: unclearROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 0 RCTRCT 7.00[0.29; 170.06]39 -NAWelt, 1981 1 Type of controls unexposed, sickunexposed, sick 7.00[0.29; 170.06]39 -NAWelt, 1981 1 Tags Adjustment   - Randomisation  - Randomisation 7.00[0.29; 170.06]39 -NAWelt, 1981 1 Indications Antihypertensive   - Only chronic hypertension indication  - Only chronic hypertension indication 7.00[0.29; 170.06]39 -NAWelt, 1981 1 All studiesAll studies 7.00[0.29; 170.06]39 -NAWelt, 1981 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 7.00[0.29; 170.06]39 -NAWelt, 1981 10.510.01.0