| id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S15381 R63380 |
Noh - BZDs, 2022 | Abdominal wall defects | 1st trimester | population based cohort retrospective | unexposed, sick | Adjustment: Yes BZD Coexposure: Not specified | 1.08 [0.72;1.63] | 27/40,846 1,284/3,053,381 | 1,311 | 40,846 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S15330 R63138 |
Ban - Diazepam (Other indications) (Controls unexposed, disease free), 2014 | Abdominal wall malformations | 1st trimester | retrospective cohort (claims database) | unexposed, disease free excluded | Adjustment: No BZD Coexposure: No (among psychiatric (ATD and/or psychotropics) medications) Indication BZD: Psychiatric diseases (depression, anxiety, ...) |
1.84 [0.11;29.68] C excluded (control group) |
0/1,159 82/351,785 | 82 | 1,159 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S15327 R63108 |
Ban - Diazepam (Other indications) (Controls unexposed, sick), 2014 | Abdominal wall malformations | 1st trimester | retrospective cohort (claims database) | unexposed, sick | Adjustment: No BZD Coexposure: No (among psychiatric (ATD and/or psychotropics) medications) Indication BZD: Psychiatric diseases (depression, anxiety, ...) | 1.84 [0.10;34.20] C | 0/1,159 4/19,193 | 4 | 1,159 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 2 studies | 1.09 [0.73;1.64] | 1,315 | 42,005 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1: Other indications) (Controls unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 15330