| id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| S12950 R49147 |
Ostenfeld, 2022 | Spontaneous abortions (loss of pregnancy 5-22 completed gestational weeks) | 1st and 2nd trimester | population based cohort retrospective | unexposed (general population or NOS) | Adjustment: Yes Monotherapy: no or not specified | 1.04 [0.91;1.20] | 237/1,900 931/7,600 | 1,168 | 1,900 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S11789 R43376 |
Ozturk, 2016 | Miscarriages | at least 1st trimester | prospective cohort | unexposed (general population or NOS) | Adjustment: No Monotherapy: no or not specified | 4.10 [0.43;39.00] C | 1/5 15/261 | 16 | 5 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S12911 R48961 |
Djulus (Controls exposed to other antidepressants), 2006 | Spontaneous abortion (NOS) | 1st trimester | prospective cohort | exposed to other treatment, sick excluded | Adjustment: No Matched Monotherapy: no or not specified |
1.14 [0.56;2.30] C excluded (control group) |
20/104 18/104 | 38 | 104 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S12910 R48956 |
Djulus (Controls unexposed, disease free), 2006 | Spontaneous abortion (NOS) | 1st trimester | prospective cohort | unexposed, disease free | Adjustment: No Matched Monotherapy: no or not specified | 2.01 [0.91;4.45] C | 20/104 11/104 | 31 | 104 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S11269 R41409 |
Yaris, 2005 | Spontaneous abortions | during pregnancy (anytime or not specified) | prospective cohort | unexposed (general population or NOS) | Adjustment: No Monotherapy: no or not specified | 4.43 [0.48;40.72] C | 1/7 9/248 | 10 | 7 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 4 studies | 1.53 [0.83;2.85] | 1,225 | 2,016 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1: Controls unexposed, disease free;
Asymetry test p-value = NaN (by Egger's regression)
not enought points
excluded 12911