Alprazolam updated on 02-10-2025

Perinatal death

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S15641
R64553		 Kelty (Controls unexposed, disease free), 2023 Perinatal mortality during pregnancy (anytime or not specified) retrospective cohort unexposed, disease free Adjustment: No BZD Coexposure: Not specified 2.01 [0.04;102.91] C 0/48   0/96 0 48
ref
Total 1 studies 2.01 [0.04;102.91] 0 48
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Kelty (Controls unexposed, disease free), 2023Kelty, 2023 1 2.01[0.04; 102.91]0480%ROB confusion: seriousROB selection: lowROB classification: criticalROB missing: unclearROB mesure: moderateROB reporting: moderate0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Controls unexposed, disease free;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.01[0.04; 102.91]-48 -NAKelty (Controls unexposed, disease free), 2023 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 2.01[0.04; 102.91]-48 -NAKelty (Controls unexposed, disease free), 2023 1 Tags Adjustment   - No  - No 2.01[0.04; 102.91]-48 -NAKelty (Controls unexposed, disease free), 2023 1 BZD Coexposure   - Not specified  - Not specified 2.01[0.04; 102.91]-48 -NAKelty (Controls unexposed, disease free), 2023 1 All studiesAll studies 2.01[0.04; 102.91]-48 -NAKelty (Controls unexposed, disease free), 2023 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 2.01[0.04; 102.91]-48 -NAKelty (Controls unexposed, disease free), 2023 10.510.01.0