Glucagon-like peptide-1 (GLP-1) receptor agonists - Medication and Pregnancy KB

Glucagon-like peptide-1 (GLP-1) receptor agonists

Caesarean

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S18829 R80168	Lewin, 2025	Cesarean delivery	during pregnancy (anytime or not specified)	retrospective cohort (claims database)	unexposed, sick	Adjustment: No GLP1-RA indication: Type 2 diabetes (T2D)	1.25 [1.22;1.28] ^C	18,153/40,929 51,070/131,279	69,223	40,929		ref
S18782 R79925	Maya, 2025	Cesarean delivery	3 months or more before pregnancy or1st trimester excluded	retrospective cohort	unexposed (general population or NOS)	Adjustment: Yes GLP1-RA indication: Mixed (Diabetes and/or Overweight) or Unspecified Matched	0.94 [0.85;1.05] excluded (exposition period)	263/566 790/1,698	1,053	566		ref
					Total	1 studies	1.25 [1.22;1.28]		69,223	40,929
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded