Beta-blockers (All routes except ocular) (versus unexposed) - Medication and Pregnancy KB

Beta-blockers (All routes except ocular) (versus unexposed) updated on 12-17-2024

Limb reduction defects (LRD)

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S13907 R54467	Bergman - Beta-blockers, 2018	Limb reduction defects	1st trimester	case control	unexposed (general population or NOS)	Adjustment: Yes Indications Antihypertensive: All hypertensions, any indications or not specified	0.60 [0.20;1.90]	3/- 1,829/-	1,832	-		ref
					Total	1 studies	0.60 [0.19;1.85]		1,832	0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded