Beta-blockers (All routes except ocular) (versus unexposed) - Medication and Pregnancy KB

Beta-blockers (All routes except ocular) (versus unexposed) updated on 12-17-2024

Hydrocephaly

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S13907 R54463	Bergman - Beta-blockers, 2018	Hydrocephalus	1st trimester	case control	unexposed (general population or NOS)	Adjustment: Yes Indications Antihypertensive: All hypertensions, any indications or not specified	0.70 [0.30;2.00]	4/- 1,977/-	1,981	-		ref
S13785 R53985	Fisher a - Beta-blockers, 2018	Hydrocephaly	1st trimester	case control	unexposed, disease free	Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified	1.40 [0.30;4.50]	3/- 436/-	439	-		ref
					Total	2 studies	0.88 [0.40;1.91]		2,420	0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded