Beta-blockers (All routes except ocular) (versus unexposed) updated on 12-17-2024

Total anomalous pulm venous return

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S13888
R55950
Fisher - Beta-blockers (Controls unexposed, disease free), 2017 Total anomalous pulmonary venous return early pregnancy case control unexposed, disease free excluded Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified 2.94 [0.58;9.33]
excluded (control group)
3/43   -/- - 43
ref
S14244
R55962
Fisher - Beta-blockers (Controls unexposed, sick), 2017 Total anomalous pulmonary venous return early pregnancy case control unexposed, sick Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified 4.21 [0.75;15.76] 3/43   -/- - 43
ref
Total 1 studies 4.21 [0.92;19.30] 0 43
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Fisher - Beta-blockers (Controls unexposed, sick), 2017Fisher - Beta-blockers, 2017 1 4.21[0.75; 15.76]-430%ROB confusion: criticalROB selection: criticalROB classification: criticalROB missing: lowROB mesure: moderateROB reporting: moderate0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Controls unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 4.21[0.92; 19.30]-43 -NAFisher - Beta-blockers (Controls unexposed, sick), 2017 1 Type of controls unexposed, sickunexposed, sick 4.21[0.92; 19.30]-43 -NAFisher - Beta-blockers (Controls unexposed, sick), 2017 1 Tags Adjustment   - No  - No 4.21[0.92; 19.30]-43 -NAFisher - Beta-blockers (Controls unexposed, sick), 2017 1 Indications Antihypertensive   - All hypertensions, any indications ...  - All hypertensions, any indications or not specified 4.21[0.92; 19.30]-43 -NAFisher - Beta-blockers (Controls unexposed, sick), 2017 1 All studiesAll studies 4.21[0.92; 19.30]-43 -NAFisher - Beta-blockers (Controls unexposed, sick), 2017 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 13888

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 2.94[0.73; 11.79]-43 -NAFisher - Beta-blockers (Controls unexposed, disease free), 2017 1 unexposed, sick controlsunexposed, sick controls 4.21[0.92; 19.30]-43 -NAFisher - Beta-blockers (Controls unexposed, sick), 2017 10.510.01.0