Beta-blockers (All routes except ocular) (versus unexposed) updated on 12-17-2024

Large for gestational age (weight)

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S13863
R54227
Mazkereth - Beta-blockers, 2019 Large for gestational age (birth weight for gestational age >= 90th) during pregnancy (anytime or not specified) retrospective cohort unexposed, sick Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified Matched 1.85 [0.61;5.65] C 9/153   5/153 14 153
ref
Total 1 studies 1.85 [0.61;5.65] 14 153
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Mazkereth - Beta-blockers, 2019Mazkereth - Beta-blockers, 2019 1.85[0.61; 5.65]141530%ROB confusion: criticalROB selection: criticalROB classification: criticalROB missing: lowROB mesure: moderateROB reporting: moderate0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 1 Tags Adjustment   - No  - No 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 1 Indications Antihypertensive   - All hypertensions, any indications ...  - All hypertensions, any indications or not specified 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 1 MatchedMatched 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 1 All studiesAll studies 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 1.85[0.61; 5.65]14153 -NAMazkereth - Beta-blockers, 2019 10.510.01.0