Fluoxetine updated on 07-01-2025

Therapeutic terminations of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S15005
R61454		 Chambers, 1996 Therapeutic abortion 1st trimester prospective cohort unexposed (general population or NOS) Adjustment: No Monotherapy: no or not specified 5.88 [2.45;14.13] C 22/154   7/254 29 154
ref
Total 1 studies 5.88 [2.45;14.13] 29 154
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Chambers, 1996Chambers, 1996 5.88[2.45; 14.13]291540%ROB confusion: criticalROB selection: criticalROB classification: lowROB missing: lowROB mesure: moderateROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 5.88[2.45; 14.13]29154 -NAChambers, 1996 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 5.88[2.45; 14.13]29154 -NAChambers, 1996 1 Tags Adjustment   - No  - No 5.88[2.45; 14.13]29154 -NAChambers, 1996 1 Monotherapy   - no or not specified  - no or not specified 5.88[2.45; 14.13]29154 -NAChambers, 1996 1 All studiesAll studies 5.88[2.45; 14.13]29154 -NAChambers, 1996 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 5.88[2.45; 14.13]29154 -NAChambers, 1996 10.510.01.0