Paroxetine updated on 07-01-2025

Neonatal tachypnea

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S13126
R50046		 Marks (Controls exposed to Bupropion), 2021 Transient tachypnea of the newborn during pregnancy (anytime or not specified) retrospective cohort exposed to other treatment, sick Adjustment: No Monotherapy: substance alone among all Antidep (SSRI, SNRI, ...) 2.07 [0.94;4.59] C 9/55   35/406 44 55
ref
Total 1 studies 2.07 [0.94;4.59] 44 55
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Marks (Controls exposed to Bupropion), 2021Marks, 2021 1 2.07[0.94; 4.59]44550%ROB confusion: criticalROB selection: lowROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Controls exposed to Bupropion;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.07[0.94; 4.59]4455 -NAMarks (Controls exposed to Bupropion), 2021 1 case control studiescase control studies 0 Type of controls exposed to other treatment, sickexposed to other treatment, sick 2.07[0.94; 4.59]4455 -NAMarks (Controls exposed to Bupropion), 2021 1 Tags Adjustment   - No  - No 2.07[0.94; 4.59]4455 -NAMarks (Controls exposed to Bupropion), 2021 1 Monotherapy   - substance alone among all Antidep ( ...  - substance alone among all Antidep (SSRI, SNRI, ...) 2.07[0.94; 4.59]4455 -NAMarks (Controls exposed to Bupropion), 2021 1 All studiesAll studies 2.07[0.94; 4.59]4455 -NAMarks (Controls exposed to Bupropion), 2021 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls exposed to other treatment, sick controlsexposed to other treatment, sick controls 2.07[0.94; 4.59]4455 -NAMarks (Controls exposed to Bupropion), 2021 10.510.01.0