Aripiprazole updated on 06-10-2025

Elective/induced termination of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2399
R3021		 Bellet, 2015 Voluntary abortions 1st trimester prospective cohort unexposed (general population or NOS) Adjustment: No 5.78 [1.49;22.40] 8/86   3/172 11 86
ref
S2387
R2949		 Paulus, 2013 Elective termination of pregnancy 1st trimester prospective cohort unexposed (general population or NOS) Adjustment: No 7.29 [2.43;21.87] C 11/68   5/194 16 68
ref
Total 2 studies 6.65 [2.83;15.61] 27 154
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Bellet, 2015Bellet, 2015 5.78[1.49; 22.40]118640%ROB confusion: criticalROB selection: moderateROB classification: moderateROB missing: moderateROB mesure: unclearROB reporting: moderate Paulus, 2013Paulus, 2013 7.29[2.43; 21.87]166860%ROB confusion: criticalROB selection: unclearROB classification: moderateROB missing: unclearROB mesure: unclearROB reporting: unclear Total (2 studies) I2 = 0% 6.65[2.83; 15.61]271540.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 6.65[2.83; 15.61]271540%NABellet, 2015 Paulus, 2013 2 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 6.65[2.83; 15.61]271540%NABellet, 2015 Paulus, 2013 2 Tags Adjustment   - No  - No 6.65[2.83; 15.61]271540%NABellet, 2015 Paulus, 2013 2 All studiesAll studies 6.65[2.83; 15.61]271540%NABellet, 2015 Paulus, 2013 20.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 6.65[2.83; 15.61]271540%NABellet, 2015 Paulus, 2013 20.510.01.0