Lurasidone updated on 06-10-2025

Withdrawal syndrome / Neonatal abstinence syndrome / Poor neonatal adaptation

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S12460
R46747		 Kernizan, 2019 Neonatal abstinence score > 7 during pregnancy (anytime or not specified) retrospective cohort unexposed, sick Adjustment: No 0.34 [0.04;2.67] C 1/24   16/140 17 24
ref
Total 1 studies 0.34 [0.04;2.67] 17 24
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Kernizan, 2019Kernizan, 2019 0.34[0.04; 2.67]17240%ROB confusion: criticalROB selection: unclearROB classification: unclearROB missing: unclearROB mesure: unclearROB reporting: critical0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.34[0.04; 2.67]1724 -NAKernizan, 2019 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 0.34[0.04; 2.67]1724 -NAKernizan, 2019 1 Tags Adjustment   - No  - No 0.34[0.04; 2.67]1724 -NAKernizan, 2019 1 All studiesAll studies 0.34[0.04; 2.67]1724 -NAKernizan, 2019 10.110.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls Out of scale0.34[0.04; 2.67]1724 -NAKernizan, 2019 10.510.01.0