id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S2480 R3262 |
Raguideau, 2017 | Microcephaly (ICD10-Q02 and brain MRI, assessed until 24 months of age) | early pregnancy | retrospective cohort (claims database) | unexposed (general population or NOS) | Adjustment: No | 2.58 [0.16;41.43] C | 0/770 474/1,888,130 | 474 | 770 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3850 R8185 |
Boden (Control exposed to other antipsyhcotics), 2012 | Small for gestational age (head circumference < 2.3rd percentile) | during pregnancy (anytime or not specified) | population based cohort retrospective | exposed to other treatment, sick excluded | Adjustment: No |
0.42 [0.14;1.26] C excluded (control group) |
4/186 17/340 | 21 | 186 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S2408 R3070 |
Boden (Control unexposed, NOS), 2012 | Small for gestational age (head circumference < 2.3rd percentile) | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed (general population or NOS) | Adjustment: Yes | 0.62 [0.19;2.01] | 4/186 -/- | - | 186 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 2 studies | 0.77 [0.26;2.28] | 474 | 956 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Control unexposed, NOS;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 3850