Olanzapine updated on 06-10-2025

Large for gestational age (weight)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3850
R8186		 Boden (Control exposed to other antipsyhcotics), 2012 Large for gestational age (birth weight > 97.7th percentile) during pregnancy (anytime or not specified) population based cohort retrospective exposed to other treatment, sick excluded Adjustment: No 0.34 [0.07;1.54] C
excluded (control group) 		2/187   11/354 13 187
ref
S2408
R3071		 Boden (Control unexposed, NOS), 2012 Large for gestational age (birth weight > 97.7th percentile) during pregnancy (anytime or not specified) population based cohort retrospective unexposed (general population or NOS) Adjustment: Yes 0.55 [0.14;2.11] 2/187   -/- - 187
ref
Total 1 studies 0.55 [0.14;2.14] 0 187
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Boden (Control unexposed, NOS), 2012Boden, 2012 1 0.55[0.14; 2.11]-1870%ROB confusion: seriousROB selection: lowROB classification: criticalROB missing: lowROB mesure: moderateROB reporting: moderate0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Control unexposed, NOS;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.55[0.14; 2.14]-187 -NABoden (Control unexposed, NOS), 2012 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 0.55[0.14; 2.14]-187 -NABoden (Control unexposed, NOS), 2012 1 Tags Adjustment   - Yes  - Yes 0.55[0.14; 2.14]-187 -NABoden (Control unexposed, NOS), 2012 1 All studiesAll studies 0.55[0.14; 2.14]-187 -NABoden (Control unexposed, NOS), 2012 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 3850

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 0.55[0.14; 2.14]-187 -NABoden (Control unexposed, NOS), 2012 1 exposed to other treatment, sick controlsexposed to other treatment, sick controls Out of scale0.34[0.07; 1.54]13187 -NABoden (Control exposed to other antipsyhcotics), 2012 10.510.01.0