Risperidone Paliperidone updated on 06-10-2025

Gestational diabetes

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S14445
R57303		 Wang - HK cohort, 2021 Gestational diabetes mellitus (GDM; using ICD code or a clinician reported GDM) during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed, sick Adjustment: Yes 0.32 [0.04;2.48] -/-   40/340 - -
ref
S3191
R5108		 Park, 2018 Gestational diabetes at least 1st trimester retrospective cohort (claims database) unexposed, sick Adjustment: Yes 1.09 [0.70;1.70] 23/359   60/1,465 83 359
ref
S2458
R3143		 Vigod, 2015 Gestational diabetes during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed, sick Adjustment: No 1.03 [0.46;2.31] C 7/112   62/1,021 69 112
ref
Total 3 studies 1.03 [0.70;1.51] 152 471
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Wang - HK cohort, 2021Wang - HK cohort, 2021 0.32[0.04; 2.48]--3%ROB confusion: seriousROB selection: moderateROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate Park, 2018Park, 2018 1.09[0.70; 1.70]8335974%ROB confusion: moderateROB selection: lowROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate Vigod, 2015Vigod, 2015 1.03[0.46; 2.31]6911222%ROB confusion: unclearROB selection: lowROB classification: moderateROB missing: lowROB mesure: moderateROB reporting: moderate Total (3 studies) I2 = 0% 1.03[0.70; 1.51]1524710.25.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.03[0.70; 1.51]1524710%NAWang - HK cohort, 2021 Park, 2018 Vigod, 2015 3 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 1.03[0.70; 1.51]1524710%NAWang - HK cohort, 2021 Park, 2018 Vigod, 2015 3 Tags Adjustment   - No  - No 1.03[0.46; 2.31]69112 -NAVigod, 2015 1   - Yes  - Yes 0.91[0.39; 2.13]8335923%NAWang - HK cohort, 2021 Park, 2018 2 All studiesAll studies 1.03[0.70; 1.51]1524710%NAWang - HK cohort, 2021 Park, 2018 Vigod, 2015 30.15.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 1.03[0.70; 1.51]1834710%NAWang - HK cohort, 2021 Park, 2018 Vigod, 2015 30.510.01.0