Risperidone Paliperidone updated on 06-10-2025

Elective/induced termination of pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3898
R8262
Ozturk, 2016 Elective termination of pregnancy during pregnancy (anytime or not specified) retrospective cohort unexposed (general population or NOS) Adjustment: No 5.99 [0.23;153.53] C 0/2   14/275 14 2
ref
S2485
R3349
Shechtman (Unexposed control), 2009 Elective terminations during pregnancy (anytime or not specified) prospective cohort unexposed (general population or NOS) Adjustment: No 4.39 [1.25;15.44] C 5/106   5/448 10 106
ref
Total 2 studies 4.57 [1.41;14.77] 24 108
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Ozturk, 2016Ozturk, 2016 5.99[0.23; 153.53]14213%ROB confusion: criticalROB selection: unclearROB classification: moderateROB missing: lowROB mesure: moderateROB reporting: moderate Shechtman (Unexposed control), 2009Shechtman, 2009 1 4.39[1.25; 15.44]1010687%ROB confusion: criticalROB selection: moderateROB classification: unclearROB missing: unclearROB mesure: unclearROB reporting: unclear Total (2 studies) I2 = 0% 4.57[1.41; 14.77]241080.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Unexposed control;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 4.57[1.41; 14.77]241080%NAOzturk, 2016 Shechtman (Unexposed control), 2009 2 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 4.57[1.41; 14.77]241080%NAOzturk, 2016 Shechtman (Unexposed control), 2009 2 Tags Adjustment   - No  - No 4.57[1.41; 14.77]241080%NAOzturk, 2016 Shechtman (Unexposed control), 2009 2 All studiesAll studies 4.57[1.41; 14.77]241080%NAOzturk, 2016 Shechtman (Unexposed control), 2009 20.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 4.57[1.41; 14.77]241080%NAOzturk, 2016 Shechtman (Unexposed control), 2009 20.510.01.0