Atypical antipsychotics (Second generation) updated on 06-10-2025

Neonatal infections

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2294
R8226		 Vigod, 2015 Congenital or neonatal infection during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed, sick Adjustment: No Matched 0.70 [0.27;1.84] 7/1,021   10/1,021 17 1,021
ref
Total 1 studies 0.70 [0.27;1.83] 17 1,021
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Vigod, 2015Vigod, 2015 0.70[0.27; 1.84]171,0210%ROB confusion: seriousROB selection: lowROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.70[0.27; 1.83]171,021 -NAVigod, 2015 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 0.70[0.27; 1.83]171,021 -NAVigod, 2015 1 Tags Adjustment   - No  - No 0.70[0.27; 1.83]171,021 -NAVigod, 2015 1 MatchedMatched 0.70[0.27; 1.83]171,021 -NAVigod, 2015 1 All studiesAll studies 0.70[0.27; 1.83]171,021 -NAVigod, 2015 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 0.70[0.27; 1.83]171,021 -NAVigod, 2015 10.510.01.0