Atypical antipsychotics (Second generation) updated on 06-10-2025

Abruptio placentae (retroplacental hematoma)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2294
R8212		 Vigod, 2015 Placental abruption during pregnancy (anytime or not specified) retrospective cohort (claims database) unexposed, sick Adjustment: Yes Matched 2.06 [0.98;4.28] 28/1,021   16/1,021 44 1,021
ref
Total 1 studies 2.06 [0.99;4.31] 44 1,021
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Vigod, 2015Vigod, 2015 2.06[0.98; 4.28]441,0210%ROB confusion: seriousROB selection: lowROB classification: moderateROB missing: unclearROB mesure: moderateROB reporting: moderate0.95.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 2.06[0.99; 4.31]441,021 -NAVigod, 2015 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 2.06[0.99; 4.31]441,021 -NAVigod, 2015 1 Tags Adjustment   - Yes  - Yes 2.06[0.99; 4.31]441,021 -NAVigod, 2015 1 MatchedMatched 2.06[0.99; 4.31]441,021 -NAVigod, 2015 1 All studiesAll studies 2.06[0.99; 4.31]441,021 -NAVigod, 2015 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls 2.06[0.99; 4.31]441,021 -NAVigod, 2015 10.510.01.0