| id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S17090 R71458 |
Bruno - Quetiapine, 2024 | Language disorders/delay (ICD-10 codes F80.0–F80.2, in the absence of a hearing loss diagnosis) - Median follow-up: 6.7 years | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed, sick | Adjustment: Yes | 1.18 [0.94;1.49] | 96/3,894 1,773/163,604 | 1,869 | 3,894 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S12466 R46919 |
Straub, 2022 | Speech/language disorder (≥ 2 dates with ICD-9 Dx 315.3x (except 315.34)) - By 8 years of age | 2nd and/or 3rd trimester | retrospective cohort (claims database) | unexposed (general population or NOS) | Adjustment: Yes | 1.08 [0.96;1.21] | 386/9,390 76,670/3,309,095 | 77,056 | 9,390 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S2332 R2729 |
Peng, 2013 | Developmental Quotient (< 85) - Bayley-III Language scale - At 12 months of age | throughout pregnancy | prospective cohort | unexposed, disease free | Adjustment: No Matched | 1.13 [0.43;2.95] C | 10/76 9/76 | 19 | 76 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 3 studies | 1.10 [0.99;1.22] | 78,944 | 13,360 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded