Atypical antipsychotics (Second generation) updated on 06-10-2025

Macrosomia (> 4000g)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2339
R2746		 Newport, 2007 High birth weight (> 4000 g) late pregnancy prospective cohort exposed to other treatment, sick Adjustment: No 0.30 [0.02;5.17] C 1/41   1/13 2 41
ref
Total 1 studies 0.30 [0.02;5.17] 2 41
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Newport, 2007Newport, 2007 0.30[0.02; 5.17]2410%ROB confusion: criticalROB selection: unclearROB classification: lowROB missing: lowROB mesure: moderateROB reporting: moderate0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.30[0.02; 5.17]241 -NANewport, 2007 1 case control studiescase control studies 0 Type of controls exposed to other treatment, sickexposed to other treatment, sick 0.30[0.02; 5.17]241 -NANewport, 2007 1 Tags Adjustment   - No  - No 0.30[0.02; 5.17]241 -NANewport, 2007 1 All studiesAll studies 0.30[0.02; 5.17]241 -NANewport, 2007 10.110.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls exposed to other treatment, sick controlsexposed to other treatment, sick controls Out of scale0.30[0.02; 5.17]241 -NANewport, 2007 10.510.01.0