Metoclopramide

Caesarean

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2404
R3052		 Ashkenazi-Hoffnung, 2013 Cesarean section at least 1st trimester excluded prospective cohort exposed to other treatment, sick Adjustment: No 2.08 [0.35;12.45] C
excluded (exposition period) 		4/28   2/27 6 28
ref
S2732
R3603		 Neri, 2005 Cesarean section 1st trimester excluded randomized controlled trial unexposed, sick Adjustment: Randomisation Intravenous 1.83 [0.47;7.04] C
excluded (exposition period) 		6/38   4/43 10 38
ref
S2393
R2971		 Berkovitch, 2002 Cesarean section during pregnancy (anytime or not specified) prospective cohort unexposed, disease free Adjustment: No Matched 1.53 [0.92;2.55] 31/158   21/164 52 158
ref
Total 1 studies 1.53 [0.92;2.55] 52 158
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Berkovitch, 2002Berkovitch, 2002 1.53[0.92; 2.55]521580%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.55.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 1.53[0.92; 2.55]52158 -NABerkovitch, 2002 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 1.53[0.92; 2.55]52158 -NABerkovitch, 2002 1 Tags Adjustment   - No  - No 1.53[0.92; 2.55]52158 -NABerkovitch, 2002 1 MatchedMatched 1.53[0.92; 2.55]52158 -NABerkovitch, 2002 1 All studiesAll studies 1.53[0.92; 2.55]52158 -NABerkovitch, 2002 10.55.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 1.53[0.92; 2.55]52158 -NABerkovitch, 2002 10.510.01.0