Ondansetron

Low Apgar score (< 7) (at 1 min)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2861
R3998		 Marciniak, 2015 Apgar score at 1 min (< 8) late pregnancy randomized controlled trial unexposed, sick Adjustment: Randomisation Intravenous 0.47 [0.04;5.45] C 1/35   2/34 3 35
ref
Total 1 studies 0.47 [0.04;5.45] 3 35
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Marciniak, 2015Marciniak, 2015 0.47[0.04; 5.45]3350%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 0 RCTRCT 0.47[0.04; 5.45]335 -NAMarciniak, 2015 1 Type of controls unexposed, sickunexposed, sick 0.47[0.04; 5.45]335 -NAMarciniak, 2015 1 Tags Adjustment   - Randomisation  - Randomisation 0.47[0.04; 5.45]335 -NAMarciniak, 2015 1 IntravenousIntravenous 0.47[0.04; 5.45]335 -NAMarciniak, 2015 1 All studiesAll studies 0.47[0.04; 5.45]335 -NAMarciniak, 2015 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls Out of scale0.47[0.04; 5.45]335 -NAMarciniak, 2015 10.510.01.0