Renin-angiotensin system (ACEIs and/or ARBs) (versus unexposed) updated on 03-11-2025

Ectopic pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S14145
R55546
Diav-Citrin - ACEi/ARB, 2011 Ectopic pregnancy early pregnancy prospective cohort unexposed (general population or NOS) Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified Renin angiotensin: ARBs and/or ACEIs (Angiotensin II receptor blockers and/or Angiotensin-converting enzyme inhibitors) 5.92 [0.24;145.91] C 1/252   0/495 1 252
ref
Total 1 studies 5.92 [0.24;145.91] 1 252
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Diav-Citrin - ACEi/ARB, 2011Diav-Citrin - ACEi/ARB, 2011 5.92[0.24; 145.91]12520%ROB confusion: criticalROB selection: moderateROB classification: moderateROB missing: lowROB mesure: unclearROB reporting: moderate0.920.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 1 Tags Adjustment   - No  - No 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 1 Indications Antihypertensive   - All hypertensions, any indications ...  - All hypertensions, any indications or not specified 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 1 Renin angiotensin   - ARBs and/or ACEIs (Angiotensin II r ...  - ARBs and/or ACEIs (Angiotensin II receptor blockers and/or Angiotensin-converting enzyme inhibitors) 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 1 All studiesAll studies 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 10.520.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 5.92[0.24; 145.91]1252 -NADiav-Citrin - ACEi/ARB, 2011 10.510.01.0