Etanercept

Ectopic pregnancy

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S4994
R13064		 Drechsel, 2020 Ectopic pregnancy 1st trimester prospective cohort unexposed, sick Adjustment: No 22.04 [0.85;573.89] C 1/13   0/85 1 13
ref
Total 1 studies 22.04 [0.85;573.89] 1 13
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Drechsel, 2020Drechsel, 2020 22.04[0.85; 573.89]1130%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.950.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 22.04[0.85; 573.89]113 -NADrechsel, 2020 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 22.04[0.85; 573.89]113 -NADrechsel, 2020 1 Tags Adjustment   - No  - No 22.04[0.85; 573.89]113 -NADrechsel, 2020 1 All studiesAll studies 22.04[0.85; 573.89]113 -NADrechsel, 2020 10.550.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed, sick controlsunexposed, sick controls Out of scale22.04[0.85; 573.89]113 -NADrechsel, 2020 10.510.01.0