| id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S4893 R12915 |
Broms (Controls exposed to other treatments), 2020 | Small for gestation age (sex-specific weight by gestational age in the 10th percentile or below 2 standard deviations) | 3 months (or more) before pregnancy or during pregnancy | population based cohort retrospective | exposed to other treatment, sick excluded | Adjustment: No |
1.07 [0.72;1.58] C excluded (control group) |
29/257 998/9,393 | 1,027 | 257 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S4892 R12910 |
Broms (Controls unexposed, disease free), 2020 | Small for gestation age (sex-specific weight by gestational age in the 10th percentile or below 2 standard deviations) | 3 months (or more) before pregnancy or during pregnancy excluded | population based cohort retrospective | unexposed, disease free | Adjustment: No |
1.16 [0.79;1.70] C excluded (exposition period) |
29/257 160,698/1,623,483 | 160,727 | 257 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S5066 R13187 |
De Lorenzo (Controls unexposed, disease free), 2020 | Small for gestational age | at least 1st trimester | retrospective cohort | unexposed, disease free excluded | Adjustment: No |
3.10 [0.10;91.39] C excluded (control group) |
0/2 3/36 | 3 | 2 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S5067 R13193 |
De Lorenzo (Controls unexposed, sick), 2020 | Small for gestational age | at least 1st trimester | retrospective cohort | unexposed, sick | Adjustment: No | 3.93 [0.12;124.06] C | 0/2 2/32 | 2 | 2 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S5069 R13221 |
Chambers (Controls unexposed, disease free), 2019 | Weight < 10th centile for Gestational Age At Birth | at least 1st trimester | prospective cohort | unexposed, disease free excluded | Adjustment: Yes |
1.07 [0.52;2.21] excluded (control group) |
17/206 15/192 | 32 | 206 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S5068 R13206 |
Chambers (Controls, sick), 2019 | Weight < 10th centile for Gestational Age At Birth | at least 1st trimester | prospective cohort | unexposed, sick | Adjustment: No | 0.75 [0.37;1.54] | 17/206 11/100 | 28 | 206 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 2 studies | 0.80 [0.40;1.61] | 30 | 208 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1: Controls unexposed, sick; 2: Controls, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 5069, 4893, 5066