TNF-alpha inhibitors

Child/Infant infections (> 1 year)

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
Chaparro, 2018 Severe infections (admission to hospital at any time during follow-up, i.e Median: 68 months (13–216)) 3 months (or more) before pregnancy or during pregnancy excluded retrospective cohort unexposed, sick Adjustment: No 1.25 [0.81;1.94] C
excluded (exposition period)
46/388   44/453 90 388
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis