TNF-alpha inhibitors

Cardiac septal defects

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3194
R8742
Bröms a (Controls unexposed, disease free), 2016 Cardiac septal defects 3 months or more before pregnancy or1st trimester population based cohort retrospective unexposed, disease free excluded Adjustment: No 2.00 [1.20;3.33] C
excluded (control group)
15/683   13,901/1,250,192 13,916 683
ref
S3193
R8743
Bröms a (Controls unexposed, sick), 2016 Cardiac septal defects 3 months or more before pregnancy or1st trimester excluded population based cohort retrospective unexposed, sick Adjustment: No 1.75 [1.03;2.96] C
excluded (exposition period)
15/683   273/21,549 288 683
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis