| id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S4098 R8754 |
Carman - Etanercept (Controls unexposed, disease free), 2017 | Oral‐facial malformations | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | unexposed, disease free excluded | Adjustment: No |
5.17 [0.72;36.93] C excluded (control group) |
2/210 2/1,078 | 4 | 210 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S4099 R8769 |
Carman - Etanercept (Controls unexposed, sick), 2017 | Oral‐facial malformations | during pregnancy (anytime or not specified) excluded | retrospective cohort (claims database) | unexposed, sick | Adjustment: No |
9.28 [1.30;66.22] C excluded (exposition period) |
2/210 2/1,932 | 4 | 210 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S3194 R5161 |
Bröms a (Controls unexposed, disease free), 2016 | Cleft, lip, palate | 3 months or more before pregnancy or1st trimester | population based cohort retrospective | unexposed, disease free excluded | Adjustment: No |
0.41 [0.03;6.51] C excluded (control group) |
0/683 2,248/1,250,192 | 2,248 | 683 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S3193 R5139 |
Bröms a (Controls unexposed, sick), 2016 | Cleft, lip, palate | 3 months or more before pregnancy or1st trimester excluded | population based cohort retrospective | unexposed, sick | Adjustment: Yes |
0.43 [0.03;7.04] C excluded (exposition period) |
0/683 36/21,549 | 36 | 683 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 0 studies | NaN [NaN;NaN] | 0 | 0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||