Carbimazole, Thiamazole (Methimazole)

Caesarean

id	Study   Auto Gianetti (control exposed to PTU), 2015Gianetti (control unexposed, sick), 2015	Lib. in paper	Exposition period  Auto during pregnancy (anytime or not specified)1st trimester2nd trimester3rd trimester2nd and/or 3rd trimesterthroughout pregnancyearly pregnancydays before deliverylate pregnancypreconception-onlypericonceptionalpreconceptional for kinetic reasonat least 1st trimester3 months (or more) before pregnancy or during pregnancy1st and 2nd trimester3 months or more before pregnancy or1st trimester	Study type  All studies Case control excluded Only case control	Control type    Auto unexposed (general population or NOS)unexposed, sickunexposed, disease freeexposed to other treatment, sicknot specifiedsiblingwhatever (meta-analysis)	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S3563 R7096	Gianetti (control exposed to PTU), 2015	Non vaginal delivery	at least 1st trimester	retrospective cohort	exposed to other treatment, sick excluded	Adjustment: No	0.63 [0.28;1.45] C excluded (control group)	18/124   11/52	29	124		ref
S3562 R7085	Gianetti (control unexposed, sick), 2015	Non vaginal delivery	at least 1st trimester excluded	retrospective cohort	unexposed, sick	Adjustment: No	0.40 [0.22;0.71] C excluded (exposition period)	18/124   61/203	79	124		ref
					Total	0 studies	NaN [NaN;NaN]		0	0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis