Thiouracil, propylthiouracil, benzylthiouracil

Cardiac septal defects

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S8718
R29460
Korelitz (control exposed to MMI), 2013 Atrial or ventricular septal heart defects (ASD/VSD) 3 months (or more) before pregnancy or during pregnancy retrospective cohort (claims database) exposed to other treatment, sick excluded Adjustment: No 1.54 [0.20;11.91] C
excluded (control group)
13/915   1/108 14 915
ref
S3387
R6309
Korelitz (control exposed to MMI), 2013 Atrial or ventricular septal heart defects (ASD/VSD) 3 months (or more) before pregnancy or during pregnancy retrospective cohort (claims database) exposed to other treatment, sick excluded Adjustment: No 1.54 [0.20;11.91] C
excluded (control group)
13/915   1/108 14 915
ref
S3388
R6317
Korelitz (control unexposed, disease free), 2013 Atrial or ventricular septal heart defects (ASD/VSD) 3 months (or more) before pregnancy or during pregnancy retrospective cohort (claims database) unexposed, disease free excluded Adjustment: No 1.13 [0.66;1.96] C
excluded (control group)
13/915   7,970/634,858 7,983 915
ref
S3389
R6325
Korelitz (control unexposed, sick), 2013 Atrial or ventricular septal heart defects (ASD/VSD) 3 months (or more) before pregnancy or during pregnancy excluded retrospective cohort (claims database) unexposed, sick Adjustment: No 1.10 [0.59;2.05] C
excluded (exposition period)
13/915   42/3,236 55 915
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis