id  Study  Lib. in paper  Exposition period  Study type 
Control type 
Tags  OR 95%CI  x1/n1 x0/n0  no cases  no exposed  ROB  Ref.  

S3359 R6107 
Howley, 2017  Craniosynostosis  1st trimester  case control  unexposed, disease free  Adjustment: No  1.47 [0.32;6.73] ^{C}  2/12 1,532/12,822  1,534  12 

ref  
S3355 R6077 
Yoshihara (control exposed to MMI), 2012  Craniosynostosis  1st trimester  retrospective cohort  exposed to other treatment, sick excluded  Adjustment: No 
0.29 [0.01;7.20] ^{C} excluded (control group) 
0/1,399 1/1,231  1  1,399 

ref  
S3354 R6034 
Yoshihara (control unexposed, sick), 2012  Craniosynostosis  1st trimester  retrospective cohort  unexposed, sick  Adjustment: No  0.45 [0.02;11.15] ^{C}  0/1,399 1/1,906  1  1,399 

ref  
Total  2 studies  1.19 [0.30;4.68]  1,535  1,411  
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^{C:} calculated odds ratio from numbers of events and effectives 
1: control unexposed, sick;
Funnel plot not drawn. Less than 3 points.
Asymetry test pvalue = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 3355