id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S3441 R6399 |
Zhang, 2016 | Preterm birth (≥28 but <37 weeks) | during pregnancy (anytime or not specified) | retrospective cohort | unexposed, sick | Adjustment: No | 0.60 [0.09;3.94] C | 3/43 2/18 | 5 | 43 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3564 R7106 |
Gianetti (control exposed to MMI), 2015 | Preterm | at least 1st trimester | retrospective cohort | exposed to other treatment, sick excluded | Adjustment: No |
0.79 [0.08;7.78] C excluded (control group) |
1/52 3/124 | 4 | 52 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3565 R7117 |
Gianetti (control unexposed, sick), 2015 | Preterm | throughout pregnancy | retrospective cohort | unexposed, sick | Adjustment: No | 0.38 [0.05;3.03] C | 1/52 10/203 | 11 | 52 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3346 R5819 |
Chen (Control exposed to MMI), 2011 | Preterm birth, birth >24 and <37 weeks of gestation | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | exposed to other treatment, sick excluded | Adjustment: No |
0.55 [0.26;1.17] C excluded (control group) |
45/630 9/73 | 54 | 630 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3347 R5823 |
Chen (control unexposed, disease free), 2011 | Preterm birth, birth >24 and <37 weeks of gestation | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | unexposed, disease free excluded | Adjustment: No |
1.09 [0.80;1.48] C excluded (control group) |
45/630 934/14,150 | 979 | 630 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3348 R5827 |
Chen (control unexposed, sick), 2011 | Preterm birth, birth >24 and <37 weeks of gestation | during pregnancy (anytime or not specified) | population based cohort retrospective | unexposed, sick | Adjustment: Yes | 0.92 [0.66;1.31] | 45/630 162/2,127 | 207 | 630 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3374 R6205 |
Rosenfeld, 2009 | Preterm delivery (<37 weeks) | during pregnancy (anytime or not specified) | prospective cohort | unexposed (general population or NOS) | Adjustment: No | 1.84 [0.91;3.72] C | 10/100 58/1,018 | 68 | 100 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S3456 R6571 |
Dwarakanath (control exposed to MMI), 1999 | Preterm labour | throughout pregnancy | retrospective cohort | exposed to other treatment, sick | Adjustment: No | 1.00 [0.02;58.44] C | 0/7 0/7 | 0 | 7 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 5 studies | 1.03 [0.73;1.46] | 291 | 832 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: control unexposed, sick; 2: control unexposed, sick; 3: control exposed to MMI;
Asymetry test p-value = 0.8422 (by Egger's regression)
slope=0.0577 (0.2727); intercept=-0.1727 (0.7963); t=0.2169; p=0.8422
excluded 3346, 3347, 3564