Zolmitriptan

Neonatal medical care

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3589
R7263
Nezvalová-Henriksen (Control unexposed, disease free), 2013 Neonate transferred to intensive care 3rd trimester population based cohort retrospective unexposed, disease free excluded Adjustment: No 3.39 [1.11;10.41] C
excluded (control group)
4/17   14,848/178,565 14,852 17
ref
S3590
R7280
Nezvalová-Henriksen (Control unexposed, sick), 2013 Neonate transferred to intensive care 3rd trimester population based cohort retrospective unexposed, sick Adjustment: No 3.89 [1.08;13.95] C 4/17   11/150 15 17
ref
Total 1 studies 3.89 [1.08;13.95] 15 17
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Nezvalová-Henriksen (Control unexposed, sick), 2013Nezvalová-Henriksen, 2013 1 3.89[1.08; 13.95]15170%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.910.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Control unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 3.89[1.08; 13.95]1517 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 3.89[1.08; 13.95]1517 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 Tags Adjustment   - No  - No 3.89[1.08; 13.95]1517 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 All studiesAll studies 3.89[1.08; 13.95]1517 -NANezvalová-Henriksen (Control unexposed, sick), 2013 10.510.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 3589

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 3.39[1.11; 10.41]14,85217 -NANezvalová-Henriksen (Control unexposed, disease free), 2013 1 unexposed, sick controlsunexposed, sick controls 3.89[1.08; 13.95]1517 -NANezvalová-Henriksen (Control unexposed, sick), 2013 10.510.01.0