Rizatriptan

Preterm (< 37 weeks)

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3583
R7185
Nezvalová-Henriksen (Control unexposed, disease free), 2013 Gestational age < 37 weeks during pregnancy (anytime or not specified) population based cohort retrospective unexposed, disease free excluded Adjustment: Yes 0.67 [0.42;1.08]
excluded (control group)
18/334   13,013/178,565 13,031 334
ref
S3584
R7202
Nezvalová-Henriksen (Control unexposed, sick), 2013 Gestational age < 37 weeks during pregnancy (anytime or not specified) population based cohort retrospective unexposed, sick Adjustment: No 0.48 [0.26;0.88] C 18/334   29/271 47 334
ref
Total 1 studies 0.48 [0.26;0.88] 47 334
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Nezvalová-Henriksen (Control unexposed, sick), 2013Nezvalová-Henriksen, 2013 1 0.48[0.26; 0.88]473340%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Control unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.48[0.26; 0.88]47334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 0.48[0.26; 0.88]47334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 Tags Adjustment   - No  - No 0.48[0.26; 0.88]47334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 All studiesAll studies 0.48[0.26; 0.88]47334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 3583

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 0.67[0.42; 1.07]13,031334 -NANezvalová-Henriksen (Control unexposed, disease free), 2013 1 unexposed, sick controlsunexposed, sick controls Out of scale0.48[0.26; 0.88]47334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 10.510.01.0