Rizatriptan

Low birth weight (< 2500g)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3583
R7182		 Nezvalová-Henriksen (Control unexposed, disease free), 2013 Birth weight < 2,500 g during pregnancy (anytime or not specified) population based cohort retrospective unexposed, disease free excluded Adjustment: Yes 1.11 [0.67;1.82]
excluded (control group) 		16/334   7,168/178,565 7,184 334
ref
S3584
R7199		 Nezvalová-Henriksen (Control unexposed, sick), 2013 Birth weight < 2,500 g during pregnancy (anytime or not specified) population based cohort retrospective unexposed, sick Adjustment: No 0.75 [0.37;1.52] C 16/334   17/271 33 334
ref
Total 1 studies 0.75 [0.37;1.52] 33 334
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Nezvalová-Henriksen (Control unexposed, sick), 2013Nezvalová-Henriksen, 2013 1 0.75[0.37; 1.52]333340%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

1: Control unexposed, sick;

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.75[0.37; 1.52]33334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 case control studiescase control studies 0 Type of controls unexposed, sickunexposed, sick 0.75[0.37; 1.52]33334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 Tags Adjustment   - No  - No 0.75[0.37; 1.52]33334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 1 All studiesAll studies 0.75[0.37; 1.52]33334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded 3583

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 1.11[0.67; 1.83]7,184334 -NANezvalová-Henriksen (Control unexposed, disease free), 2013 1 unexposed, sick controlsunexposed, sick controls 0.75[0.37; 1.52]33334 -NANezvalová-Henriksen (Control unexposed, sick), 2013 10.510.01.0