Calcium channel blockers (versus unexposed) - Medication and Pregnancy KB

Calcium channel blockers (versus unexposed)

Oesophageal atresia with or without tracheo-oesophageal fistula

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S13787 R54030	Fisher a - Calcium blockers, 2018	Esophageal atresia	1st trimester	case control	unexposed, disease free	Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified	1.15 [0.15;8.74] ^C	1/15 657/11,214	658	15		ref
S13996 R54979	Sorensen - Calcium blockers, 2001	Esophageal atresia/stenosis	1st trimester	case control	unexposed (general population or NOS)	Adjustment: No Indications Antihypertensive: All hypertensions, any indications or not specified	1.80 [0.11;29.32] ^C	0/49 214/38,316	214	49		ref
					Total	2 studies	1.34 [0.26;6.93]		872	64
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded